Cosmelan Peel treatment for severe pigmentation
The Cosmelan MD Depigmentation Treatment consists of two phases. It is imperative that both be used according to direction to achieve complete success. Cosmelan MD Depigmentation Treatment offers a non-invasive depigmentation action for all skin types. Highly effective for all kinds of hyperpigmentation (Melasma, Chloasma, Sun damage and Post inflammatory pigmentation


  • Very effective in all types of melasma
  • Rapid and easy depigmentation action
  • Compatible with all skin types (Fitzpatrick IV)
  • Light peeling effect
  • Rejuvenates the skin
  • Treatment can be used all year round
  • Beneficial for acne patients
  • Does not contain TCA
  • High safety margin

In 99% of the cases, the disappearance of the blemishes improves by 95%….
One week after starting the Cosmelan MD Depigmentation Treatment, a noticeable significant improvement of the skin is observed. The reduction of the treated blemish is detected and the appearance of new luminous and rejuvenated skin is present.
At the end of the Cosmelan MD Depigmentation Treatment, the blemishes start to disappear altogether. Although the patient may be able to locate the place where the spot was, in truth the pigmentation will have disappeared and nobody will be able to see it just by looking at it.

The process consists of two parts. The first stage is applied in your physician’s office and involves cleansing the skin and application of a yellow mustard color mask (Cosmelan 1). The mask will be left on for a total of 4-8 hours depending on your skin type. You will go home with the mask on.
After the action time has elapsed, you will remove the mask with water and a neutral cleanser. Immediately following the face cleansing, you will apply Mesoestetic Hydra-vital factor K cream. The second stage is home maintenance. It consists of the daily application and continual use of the Cosmelan 2 cream. The cream is applied three times a day for the first week after application of the mask, then twice a day the second week, and once a day the third week onward.

What should I expect on my first day and second day after the Cosmelan mask?
During the first two days of treatment, the skin may turn red. If the skin is very sensitive, the patient may experience an itching feeling. Slight burning and tightening of the skin is absolutely normal, especially during the first 24 to 48 hours after starting the treatment. To relieve these problems, it is advisable to apply the Mesoestetic Hydra-vital factor K whenever necessary.
What should I expect on my third and fourth day?
After the third or fourth day, the skin appears healthy and luminous and the marks begin to fade.
Reddening of the skin?
The reddening that occurs on the face after applying the Mesoestetic Cosmelan 1 treatment is similar to the effects of day-long exposure to the sun in the snow without protection.
Flaking may occur on all skin types (and more intensely in photo types I and II) between the second and third day. In this case it is advisable to apply the Mesoestetic Hydra-vital factor K cream, repeating this every two hours on the day when flaking is most intense.

Cosmelan 1 – Cream (10g)
Azelaic Acid, Kojic Acid, Phytic Acid, Ascorbic Acid, Arbutine, Titanium Dioxide. A prescription strength hydroquinone may be added on request.
Cosmelan 2 – Maintenance Cream (30g)
Titanium Dioxide, Kojic Acid, Phytic Acid, Ascorbic Acid and hydroquinone on request.

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